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| Registros recuperados: 104 | |
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| Zhang, Houshuang; Lee, Eung-goo; Liao, Min; Compaore, Muller K.A.; Zhang, Guohong; Kawase, Osamu; Fujisaki, Kozo; Sugimoto, Chihiro; Nishikawa, Yoshifumi; Xuan, Xuenan. |
| The characterization of the cross-reactive antigens of two closely related apicomplexan parasites, Neospora caninum and Toxoplasma gondii, is important to elucidate the common mechanisms of parasite–host interactions. In this context, a gene encoding N. caninum ribosomal phosphoprotein P0 (NcP0) was identified by immunoscreening of a N. caninum tachyzoite cDNA expression library with antisera from mice immunized with T. gondii tachyzoites. The NcP0 was encoded by a gene with open reading frame of 936 bp, which encoded a protein of 311 amino acids. The NcP0 gene existed as a single copy in the genome and was interrupted by a 432 bp intron. The NcP0 showed 94.5% amino acid identity to T. gondii P0 (TgP0). Anti-recombinant NcP0 (rNcP0) sera recognized a... |
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Palavras-chave: Neospora caninum; Toxoplasma gondii; Ribosomal phosphoprotein P0; Cross-reactive. |
| Ano: 2007 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/1035 |
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| Santos, João Paulo de Almeida Ferreira dos; Nasciutti, Nayara Resende; Oliveira, Patricia Magalhães de; Anjos, Carolina; Garcia, Felipe Gonçalves. |
| O Toxoplasma gondii é um parasita que tem como hospedeiro definitivo todos os felídeos, e como hospedeiros intermediários os mamíferos, dentre eles o próprio felídeo, o homem e o equino. A contaminação nos herbívoros ocorre pela ingestão de gramíneas e ração contaminadas pelo oocisto. Foi atendido no Hospital Veterinário da Universidade Federal de Uberlândia um equino, macho, quarto de milha, de dois anos e meio de idade, com histórico de fezes pastosas, emagrecimento e incoordenação nos membros posteriores. Ficava com uma égua em um piquete, que morreu dez dias antes com os mesmo sinais clínicos, sendo a alimentação a base de pasto e sal mineral e água em cocho. No hemograma foi constatado anemia, sendo também realizado diagnóstico diferencial para anemia... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cavalo; Elisa; Toxoplasma gondii. |
| Ano: 2015 |
URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/25234 |
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| Gazzinelli,R.T.; Talvani,A.; Camargo,M.M.; Santiago,H.C.; Oliveira,M.A.P.; Vieira,L.Q.; Martins,G.A.; Aliberti,J.C.S.; Silva,J.S.. |
| Toxoplasma gondii and Trypanosoma cruzi are intracellular parasites which, as part of their life cycle, induce a potent cell-mediated immunity (CMI) maintained by Th1 lymphocytes and IFN-<FONT FACE="Symbol">g</font>. In both cases, induction of a strong CMI is thought to protect the host against rapid parasite multiplication and consequent pathology and lethality during the acute phase of infection. However, the parasitic infection is not eliminated by the immune system and the vertebrate host serves as a parasite reservoir. In contrast, Leishmania sp, which is a slow growing parasite, appears to evade induction of CMI during early stages of infection as a strategy for surviving in a hostile environment (i.e., inside the macrophages which are... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Leishmania; Toxoplasma gondii; Trypanosoma cruzi; Macrophages; Cytokines; Nitric oxide. |
| Ano: 1998 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000100012 |
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| Mahmoud, Motamed Elsayed; Fereig, Ragab; Nishikawa, Yoshifumi. |
| Toxoplasma gondii is a pathogen relevant to psychiatric disorders. We recently showed that reactivation of chronic T. gondii infection induced depression-like behaviors in mice. Furthermore, it has been hypothesized that depression-like behaviors are mediated via a host defense mechanism against invading pathogens; proximate mechanisms of this behavioral hypothesis remain unclear. In the present study, we investigate the contribution of indoleamine 2,3-dioxygenase (IDO), inflammation, and interferon gamma (IFN-gamma) to anhedonic and despair-related behaviors in T. gondii-infected mice by using sucrose preference and forced-swim tests, respectively. First, we confirmed that BALB/c mice exhibited both sickness and depression-like behaviors during acute... |
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Palavras-chave: Toxoplasma gondii; 1-methyl tryptophan; Minocycline; Interferon gamma; Sickness behavior; Anhedonic behavior; Despair-like behavior. |
| Ano: 2017 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4507 |
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| Majidiani,Hamidreza; Dalvand,Sahar; Daryani,Ahmad; Galvan-Ramirez,Ma de la Luz; Foroutan-Rad,Masoud. |
| ABSTRACT Introduction: The global protozoan parasite, Toxoplasma gondii, infects many warm-blooded animals and humans by employing different transmission routes. There have been some recent studies on the probable relevance of infectious agents and diabetes. Therefore, we conducted a systematic review and meta-analysis to identify the possible association between chronic toxoplasmosis and diabetes mellitus. Methods: This study was conducted following the general methodology recommended for systematic reviews and meta-analysis. Nine English literature databases (Google scholar, PubMed, Scopus, Web of science, Science Direct, Ovid, ProQuest, IngentaConnect, and Wiley Online Library) were searched, up to January 2016. Random effects model was used to... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Toxoplasma gondii; Diabetes mellitus; Systematic review; Meta-analysis. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000600605 |
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| Picka,M. C. M.; Calvi,S. A.; Lima,C. R. G.; Santos,I. A. T.; Marcondes-Machado,J.. |
| Acute infection by Toxoplasma gondii leads to suppression of cell-mediated immunity, facilitating chronic infection. One of the causes of immunosuppression is Interleukin-10 (IL-10) production. Glucan is used to stimulate phagocytosis. Our objective was to study IL-10 induction in male BALB/c mice with acute T. gondii BTU-2 strain infection, glucan immunostimulation, and sulfadiazine treatment. Animals were distributed into 7 groups: G1: infected with T. gondii; G2: infected with T. gondii and treated with sulfadiazine; G3: infected with T. gondii and immunostimulated with glucan; G4: infected with T. gondii, immunostimulated with glucan, and treated with sulfadiazine; G5: imunostimulated with glucan; G6: treated with saline; and G7: treated with... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Toxoplasma gondii; Interleukin-10; Glucan; Immune response; Sulfadiazine. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992005000400012 |
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| Portella,Luiza Pires; Cadore,Gustavo Cauduro; Sangioni,Luis Antonio; Alves,Marta Elena Machado; Chemeris,Raiza; Brum,Larissa Picada; Vogel,Fernanda Silveira Flores. |
| ABSTRACT: Infections caused by protozoa belonging to the Sarcocystidae family have worldwide distribution and are common in ruminants, leading to considerable economic losses. This study evaluates Sarcocystis spp., Toxoplasma gondii and Neospora caninum infections in sheep from Southwest region of Rio Grande do Sul, Brazil. Myocardium samples of 80 sheep raised on extensive system were collected. Tissue cysts were detected by direct examination and presence of infective agents was confirmed by PCR. Macroscopic evaluation did not reveal changes, but direct microscopic examination showed cysts in 76.2% (61/80, 95% CI: 66.9 - 85.9) samples, and all cysts were morphologically similar to those caused by Sarcocystis tenella or Sarcocystis arieticanis. PCR... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Sarcocystis spp.; Toxoplasma gondii; Neospora caninum; PCR; Diagnosis. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016000901613 |
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| Camilo,Lilian Muniz; Pereira-Chioccola,Vera Lucia; Gava,Ricardo; Meira-Strejevitch,Cristina da Silva; Vidal,Jose Ernesto; Mattos,Cinara Cássia Brandão de; Frederico,Fábio Batista; De Mattos,Luiz Carlos; Spegiorin,Lígia Cosentino Junqueira Franco; Murata,Fernando Henrique Antunes; Ferreira,Marina Neves; Barbosa,Deusenia Machado Ulisses; Gonçalves,Fausto da Silva; Dias,Cristiane Moraes; Catelan,Marcia Wakai; Siqueira,Rubens Camargo; Previato,Mariana; Barbosa,Amanda Pires; Cavallini,Danilo. |
| ABSTRACT Symptomatic forms of toxoplasmosis are a serious public health problem and occur in around 10-20% of the infected people. Aiming to improve the molecular diagnosis of symptomatic toxoplasmosis in Brazilian patients, this study evaluated the performance of real time PCR testing two primer sets (B1 and REP-529) in detecting Toxoplasma gondii DNA. The methodology was assayed in 807 clinical samples with known clinical diagnosis, ELISA, and conventional PCR results in a 9-year period. All samples were from patients with clinical suspicion of several features of toxoplasmosis. According to the minimum detection limit curve (in CT), REP-529 had greater sensitivity to detect T. gondii DNA than B1. Both primer sets were retrospectively evaluated using 515... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Toxoplasma gondii; Symptomatic toxoplasmosis; Diagnosis; Real-time polymerase chain reaction. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000600638 |
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| Baldone,Valeria Natalia; Fuchs,Lumila Ivana; Rojas,María del Carmen; Fort,Marcelo Cristian; Venturini,Cecilia; Giménez,Hugo Daniel. |
| El objetivo de este trabajo fue determinar la prevalencia a Neospora caninum (Nc) y Toxoplasma gondii (Tg) y conocer el periodo reproductivo de la liebre europea (Lepus europaeus) en la provincia de La Pampa (Argentina). Para ello se muestrearon 106 liebres procedentes de acopiadores de la provincia de La Pampa. Los sueros fueron analizados por un ensayo inmunoenzimático de competición para determinar anticuerpos a Nc y para Tg se realizó una prueba de hemaglutinación indirecta. Se encontraron 66 hembras, de las cuales 13 estaban preñadas, y 40 machos (p=0,01). Sobre un total de 44 sueros analizados para Nc, 5 (11,4%) dieron positivo. De los 106 sueros estudiados para Tg ninguno fue positivo. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Animales silvestres; Ensayo inmunoenzimático; Hemaglutinación indirecta; Neospora caninum; Toxoplasma gondii. |
| Ano: 2009 |
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0325-29572009000400009 |
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| Grandía,Raiden; Entrena,Ángel; Cruz,Jeddú; Ginorio,Dora; Domenech,Ingrid; Alfonso,Abdulahi; Perdomo,Loreley; Chi,Lourdes; Burón,Miriam. |
| En ocasiones, la prevalencia de Toxoplasma gondii está asociada con la baja percepción del riesgo de infección de este protozoo en la población humana, lo cual pudiera también influir negativamente sobre sus mascotas. Por ello, se trazó como objetivo determinar el nivel de conocimiento sobre toxoplasmosis en propietarios y su asociación con la seroprevalencia en Felis catus en La Habana. Se entrevistaron los 300 propietarios de los gatos muestreados para obtener respuestas a 10 preguntas relacionadas con: etiología, transmisión, sistema de órganos afectados, diagnóstico y control. Se realizó un análisis de frecuencia para determinar el nivel de conocimiento general y por temáticas (para el primero se asignaron 10 puntos a cada respuesta correcta, 100 en... |
| Tipo: Journal article |
Palavras-chave: Desconocimiento; Propietarios; Toxoplasma gondii; Seroprevalencia; Felis catus. |
| Ano: 2013 |
URL: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0253-570X2013000200008 |
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| Rodrigues,ACF; Uezato,S; Vono,MB; Pandossio,T; Spegiorin,LCJF; Oliani,AH; Vaz Oliani,DCM; Brandão de Mattos,CC; de Mattos,LC. |
| Toxoplasma gondii infects humans through the gastrointestinal tract (GIT), which elicits humoral immune response with specific antibodies. The expression of the ABO blood group glycoconjugates also occurs in this same system and may influence the human susceptibility of infection by T. gondii. The aim of the present study was to investigate the association between ABO blood group phenotypes and the presence of anti-T. gondii antibodies. Data - including age, results of serology tests for T. gondii infection and ABO blood group phenotypes - were assembled from the medical records of 1,006 pregnant women attended in the Base Hospital of the Medical School of São José do Rio Preto, Brazil, between 2001 and 2004. The chi-square test was used to compare the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Human blood groups; Toxoplasma gondii; Toxoplasmosis; ABO blood group; Pregnant women. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992011000200009 |
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| Ogawa,L.; Freire,R.L.; Vidotto,O.; Gondim,L.F.P.; Navarro,I.T.. |
| Three-hundred and eighty-five serum samples were taken from dairy cows on 90 farms in 12 counties from the northern region of the Paraná State, Brazil. The samples were analyzed by IFAT for the detection of anti-Neospora caninum and anti-Toxoplasma gondii IgG antibodies. Forty-five (12%) samples were seropositive to N. caninum, while 102 (26%) samples were seropositive to T. gondii. Only four animals were seropositive to both coccidia. No significant difference was observed between the N. caninum serology and any of the variables studied, such as dairy cattle management, milk production, reproductive problems, feeding, and presence of dogs, cats and rodents. These data suggest that neosporosis is present among dairy cattle in the studied geographic region... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dairy cattle; Seroepidemiology; Neospora caninum; Toxoplasma gondii. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352005000300006 |
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| Gondim,Maria Fernanda Naegeli; Acosta,Igor da Cunha Lima; Rangel,Maria Cristina Valdetaro; Soares,Herbert Sousa; Gennari,Solange Maria; Dubey,Jitender Prakash; Cubas,Zalmir Silvino; Moraes,Wanderlei de; Chaparro,Francisco Javier Sosa; Barreto,Francisco Candido Cardoso; Rossi Junior,João Luiz. |
| ABSTRACT: Lowland Tapir ( Tapirus terrestris ) is the second largest South American land mammal. It is strictly herbivorous and its exposure to Toxoplasma gondii should be indicative of environmental contamination by oocysts.In the present study antibodies to T. gondii in 47 Brazilian tapirs maintained ex situ in 10 Brazilian and in one Paraguayan institution were sought in serum samples by the modified agglutination test (MAT ≥25). None of the animals presented clinical signs during the study. From 47 animals 35 (74.5%) were positive with titers of 25 in 8, 50 in 6, 100 in 12, 200 in 5, 400 in 1 and 800 in 3. One animal had samples collected on twice, and 19 were born in captivity. There was no association between occurrence of T. gondii antibodies and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ex situ; Lowland tapir; Tapirus terrestris; Toxoplasma gondii; Seroprevalence. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000300502 |
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| Fereig, Ragab M.; Nishikawa, Yoshifumi. |
| Toxoplasmosis remains a life-threatening infection of humans and various domestic and wild animals worldwide. It is caused by the obligatory intracellular protozoan parasite Toxoplasma gondii. Peroxiredoxins (Prxs) are a family of antioxidant enzymes that protect cells from oxidative stress from hydroperoxides. In the recent years, several studies have reported the potential use of T. gondii-derived enzymes in triggering protective immunity against T. gondii infection. Therefore, this study was conducted to investigate the immunogenicity and protective efficacy of TgPrx3. In vitro stimulation of peritoneal macrophages with recombinant TgPrx3 protein fused to glutathione-S transferase (TgPrx3-GST) enhanced IL-12p40 production, indicating the... |
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Palavras-chave: Toxoplasma gondii; Peroxiredoxin 3; Vaccine; Immunization. |
| Ano: 2016 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4569 |
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| Silva,Karin Lucianne Monti de Vasconcellos; La Rue,Mário Luiz de. |
| No presente trabalho, descrevem-se os resultados da detecção de anticorpos anti-T. gondii (IgG e IgM) em amostras seqüenciais de soro de cordeiros recém-nascidos e de suas mães, sem aparentes sinais clínicos da infecção. Os anticorpos IgG foram quantificados pelos testes de imunofluorescência indireta (IFI) e hemaglutinação indireta (HAI). Os anticorpos IgM foram detectados pelo método de hemaglutinação indireta 2-mercaptoetanol (HAI/ 2-ME), utilizando "kits" comerciais. Foram considerados reagentes títulos maiores ou iguais a 16, na hemaglutinação, e 20 na imunofluorescência. Coletou-se soro de 247 ovelhas e cordeiros e, após três meses, somente dos cordeiros (n=120). Do total de animais, 175 eram de uma propriedade e 72, de outra propriedade, ambas... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Toxoplasma gondii; Ovelhas; Transmissão congênita; IgG; IgM; Rosário do Sul. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782006000300025 |
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| Silva,Cassius Schnell Palhano; Neves,Elizabeth de Souza; Benchimol,Eliezer Israel; Moraes,Danielle Ribeiro de. |
| Infection caused by Toxoplasma gondii, toxoplasmosis, is one of the most frequent zoonoses in the world; it normally affects both genders equally. Humans are one of several possible intermediate hosts, and the disease is oligosymptomatic in most cases. Vertical transmission is an important cause of fetal malformation and sequels in newborns. Approximately 10% of postnatal cases present multiple manifestations, ranging from low fever and mild lymphadenopathy to severe encephalitis. In moderate cases, lesions such as retinochoroiditis may emerge during acute infection or even years later. We analyzed 313 cases of toxoplasmosis from 1992 to 2004, including 261 acute cases. Most patients were women (68.1%), and 39% of these were pregnant. Among acute infection... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Toxoplasmosis; Toxoplasma gondii; Survey; Clinical presentation; Retinochoroiditis. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000500016 |
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| Registros recuperados: 104 | |
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